Yet another sensory capability of skin has been discovered:
Biologists at the University of California, San Diego have discovered that the skin of mice can sense low levels of oxygen and regulate the production of erythropoietin, or EPO, the hormone that stimulates our bodies to produce red blood cells and allows us to adapt to high-altitude, low-oxygen environments.
“What we found in this study is really something quite unusual,” said Randall Johnson, a professor of biology at UC San Diego who headed the research study. “We discovered that mammalian skin, at least in mice, responds to how much oxygen is above it and, by virtue of that response, changes blood flow through the skin. This, in turn, changes one of the most basic responses to low oxygen that we have, which is the production of erythropoietin.”